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Cancer
can be defined as an abnormal growth of cells in any tissue or organ
of body. Cancer cells have potential to spread and grow in other
parts of the body. It preys on the host and continues to grow
indefinitely competing with normal cells of the body for nutrition.
Over
a period of time and with continued exposure to carcinogens, cancer
cells accumulate further mutations and acquire more malignant
characters such as, ability to move and invade the surrounding
tissues, ability to create new blood vessels for nourishment of
cancerous growth, ability to travel and grow in distant parts of the
body and acquire ability of limitless replication that makes cancer
cells immortal.
Chemotherapeutic
drugs may induce further mutations in cancer cells making them
resistant or refractory to the chemotherapy.
Normal
cell division is a highly regulated mechanism, which is controlled by
genes (made of DNA). Cancer causing agents(known as carcinogens)
include mutations in the growth regulatory genes by damaging DNA that
leads to loss of control over the normal cell division. It
proliferates indiscriminately usually by forming a mass known as
malignant tumour or simply 'cancer'.
The
incidence of cancer is rising alarmingly and we are constantly
exposed to a variety of carcinogens in the food we eat, the water we
drink and the air we breathe. Our single meal may contain a dozen of
carcinogens in the form of residues of pesticides and insecticides.
Radiation
emitted by X-rays, CT scans, cell phone towers, computers and other
electrical appliances have carcinogenic effect.
Likewise
there is a long list of chemical, physical and geographical
carcinogens that can cause cancer.
Transformation
of a normal cell into a cancerous cell is probably not such a
critical event in the genesis of cancer rather it is the inability of
immune cells of the body to identify and destroy the newly formed
cancer cells when they are few in numbers. It is observed that the
risk of cancer is multiplied in those persons, whose immune system is
suppressed due to other forms of serious illness they have undergone.
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